A native of Blue Springs, Missouri, Dr. Cesaretti is now in private practice in Jacksonville Florida, where he and his partners perform over 500 prostate seed implants per year. He learned his technique while a resident at Mount Sinai. He stayed on as faculty for four years during which time he studied the reasons behind why patients develop side effects during and following radiation therapy for prostate cancer. The Department of Defense awarded Dr. Cesaretti a large grant that allowed him to complete important investigations in this area. He and his research group were also awarded funding by the American Cancer Society, the National Institutes of Health, and the American Society of Therapeutic Radiology and Oncology.

Dr. Cesaretti joined FROG in 2008. He has a special interest in the application of both stereotactic body radiosurgery and prostate brachytherapy. In addition, he is a member of the Children's Oncology Group, the Annual Meeting Subcommittee of the American Society of Therapeutic Radiology and Oncology and the American Brachytherapy Society. He has given many talks about how to successfully cure prostate cancer using seed implants in Japan, South Africa, Spain, Italy, Germany, Portugal, and throughout the United States. He has authored many articles, written several protocols, and contributed the prostate brachytherapy chapter to the most recent edition of the Johns Hopkins textbook about the treatment of prostate cancer. In addition, at the 2009 World Brachytherapy Conference he served as a course instructor for the prostate seed procedure.  He also has a particular interest in helping patients make the right personal decision regarding their cancer care among an often-overwhelming array of potential treatment choices.